MEASUREMENT OF MODULUS OF CORNEA AND SCLERA USING VIBRATIONAL OPTICAL COHERENCE TOMOGRAPHY
Journal: Open Journal of Mechanical Engineering (OJME)
Author: Corey Finch
This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
A variety of methods have been used to evaluate the mechanical properties of extracellular matrix (ECM) over the last 30 years. We recently reported the use of optical coherence tomography and vibrational analysis to image and evaluate the mechanical properties of a number of ECM. The correlation between modulus measurements made on human dermis using standard tensile testing in vitro and vibrational optical coherence tomography (OCT) in vitro suggests that the two methods give similar values of the Modulus. Beyond these calibration studies, vibrational OCT has been used in vivo to image and report the differences in mechanical properties of human skin and scar tissues. In this paper, we report images and preliminary biomechanical observations of the elastic modulus of porcine and human cornea and sclera using vibrational OCT measurements on whole eyes.